Non-Antibiotic Using Novel Teat Sealant In Treating Mastitis in Dairy Cows

The image is a short representation of the formulation of a novel prevention treatment in the form of teat sealant that will protect against mastitis (an important disease of dairy cows) by not only acting as a physical barrier for the entrance of pathogenic bacteria but also acting as an antibacterial drug to kill in-vivo bacteria already residing inside the teats. Pathogens in light of consumer concerns regarding antibiotic use and bismuth neurotoxicity (present in already available sealants). We propose to treat dairy cows’ mastitis with a sealant made up of natural products from cows (host). The image describes the whole research methodology to be followed for the extraction, carrier development, sealant formulation, and in-vivo and in-vitro testing of the novel drug for developing a new intra-mammary sealant.

My current research project is titled “Non-antibiotic Approaches to Control Mastitis in Dairy Cows.” This research image is focused on developing a novel intra-mammary infusion, a sealant made up of natural products produced by cows (hosts) to treat mastitis in dairy cattle. The sealant ingredients (yellow in the image) used have been proven to lower uterine infection in dairy cows by 50% and increase milk yield by 4 liters per day. This natural sealant will be tested in Alberta on dairy cows.